NVP-BBD130

  • Chemical Properties
CAS No. 853910-61-9 Cat. No. BCP01895
Name NVP-BBD130
Synonyms NVP BBD130;NVPBBD130;
Formula C28H21N5O M. Wt 443.5
  • Biological Activity
Description IC50 values to be 72, 2336, 201 and 382 nM for PI3K p110 alpha, beta, delta and gamma isoforms, respectively; inhibition of PI3K/mTOR pathway like NVP-BEZ235, BBD130 efficiently attenuates growth and proliferation of melanoma primary tumors and metastasis.
Pathways PI3K/Akt/mTOR 
Targets PI3K 

Structure

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