VU 0152100
| CAS No. | 409351-28-6 | Cat. No. | BCP27623 |
| Name | VU 0152100 | ||
| Synonyms | VU-0152100;VU0152100; VU152100;VU 152100;VU-152100; | ||
| Formula | C18H19N3O2S | M. Wt | 341.43 |
| Description | VU0152100 is a highly selective M4 positive allosteric modulator (PAM) that exerts central effects after systemic administration. VU0152100 dose-dependently reverses amphetamine-induced hyperlocomotion in rats and wild-type mice, but not in M4 KO mice. VU0152100 also blocks amphetamine-induced disruption of the acquisition of contextual fear conditioning and prepulse inhibition of the acoustic startle reflex. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | mAChR | ||
Structure
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