Bifeprunox mesylate

  • Chemical Properties
CAS No. 350992-13-1 Cat. No. BCP02133
Name Bifeprunox mesylate
Synonyms DU-127090;DU 127090;DU127090;
Formula C24H23N3O2.CH4O3S M. Wt 481.57
  • Biological Activity
Description Active as an antipsychotic compound through activation of the serotonin 5-hydroxytryptamine (5-HT)1A receptor.Bifeprunox, also known as DU-127090, is a partial dopamine and serotonin agonist potentially for the treatment of schizophrenia. Bifeprunox influences nicotine-seeking behaviour in response to drug-associated stimuli in rats. Bifeprunox suppresses in vivo VTA dopaminergic neuronal activity via D2 and not D3 dopamine autoreceptor activation.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor Dopamine Transporter Dopamine Receptor 

Structure

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