阿哌沙班
| CAS号 | 503612-47-3 | 货号 | BCP02451 |
| 中文名 | 阿哌沙班 | ||
| 英文名 | Apixaban | ||
| 中文别名 | |||
| 英文别名 | BMS56224701; BMS 56224701; BMS-56224701; BMS562247-01;BMS 562247-01;BMS-562247-01; | ||
| 分子式 | C25H25N5O4 | 分子量 | 459.5 |
| 生物活性 | Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor Xa with Ki of 0.08 nM and 0.17 nM for Human Factor Xa and Rabbit Factor Xa, respectively.In vitro, Apixaban prolongs the clotting times of normal human plasma with the concentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT), modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highest potency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Factor Xa | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！