Sumatriptan
| CAS No. | 103628-46-2 | Cat. No. | BCP02237 |
| Name | Sumatriptan | ||
| Synonyms | Gr-43175;Gr 43175;Gr43175; | ||
| Formula | C14H21N3O2S | M. Wt | 295.4 |
| Description | Sumatriptan is structurally similar to serotonin (5-HT), and is a 5-HT receptor (types 5-HT1D and 5-HT1B[7]) agonist. Sumatriptan's primary therapeutic effect, however, is in its inhibition of the release of Calcitonin gene-related peptide (CGRP), likely through its 5-HT1D/1B receptor-agonist action.This is substantiated by the efficacy of newly developed CGRP antagonists and antibodies in the preventative treatment of migraine. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | 5 HT Receptor/Serotonin Receptor | ||
Structure
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