Purvalanol B

  • Chemical Properties
CAS No. 212844-54-7 Cat. No. BCP01952
Name Purvalanol B
Synonyms NG 95;NG95;NG-95;
Formula C20H25ClN6O3 M. Wt 432.9
  • Biological Activity
Description Purvalanol B, also known as NG 95, is a potent and selective CDK inhibitor that most potently inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively).
Pathways Cell Cycle/DNA Damage 
Targets CDK 

Structure

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