UK 383367
CAS No. | 348622-88-8 | Cat. No. | BCP02332 |
Name | UK 383367 | ||
Synonyms | UK383367;UK-383367; | ||
Formula | C15H24N4O4 | M. Wt | 324.38 |
Description | UK-383367 is effective at penetrating human skin.UK-383367 inhibits collagen deposition with IC50 of ~2 μM. UK-383367 has modest affinity for all the PDE-4 subtypes PDE-4a, PDE-4b, PDE-4c and PDE-4d with IC50 of 1.8 μM, 1.5 μM, 2.4 μM and 0.9 μM, respectively.UK-383367 is a weakly acidic compound and lipophilic. | ||
Pathways | Protease/Metabolic Enzyme | ||
Targets | Procollagen C Proteinase |
Structure
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