Nutlin-3

  • Chemical Properties
CAS No. 890090-75-2 Cat. No. BCP02265
Name Nutlin-3
Synonyms Nutlin 3;(+/-)-Nutlin3;
Formula C30H30Cl2N4O4 M. Wt 581.49
  • Biological Activity
Description Nutlin-3 is an MDM2 antagonist, inhibiting p53-Mdm2 interaction (IC50=0.09 µM) via affecting p53 binding pocket of MDM2. It has been studied in anticancer reseaches.
Pathways Apoptosis Pathway 
Targets Mdm2 p53 

Structure

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