RWJ-67657
| CAS No. | 215303-72-3 | Cat. No. | BCP01966 |
| Name | RWJ-67657 | ||
| Synonyms | RWJ67657;RWJ 67657;JNJ 3026582;JNJ-3026582;JNJ3026582; | ||
| Formula | C27H24FN3O | M. Wt | 425 |
| Description | Studies show that RWJ 67657 inhibits tyrosine kinases p56 lck and c-src, and blocks TNF-α production. RWJ 67657 has been shown to block HIV replication in T-cell and monocyte cells. Additional studies report a decrease of chemokine production, E-selectin, IL-8, and COX-2 expression in the presence of RWJ 67657. | ||
| Pathways | MAPK Pathway | ||
| Targets | p38 MAPK | ||
Structure
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