埃格列净
CAS号 | 1210344-57-2 | 货号 | BCP02525 |
中文名 | 埃格列净 | ||
英文名 | Ertugliflozin | ||
中文别名 | |||
英文别名 | PF-04971729;PF04971729;PF 04971729; PF-4971729; PF 4971729; PF4971729; PF-04971729-00; PF 04971729-00; PF04971729-00; | ||
分子式 | C22H25ClO7 | 分子量 | 436.88 |
生物活性 | Ertugliflozin, also known as also known as PF-04971729, is an inhibitor of sodium-glucose cotransporter 2 (SGLT2; IC50 = 0.927 nM for the human enzyme). clinical study showed that Ertugliflozin (1-25 mg/day) improved glycaemic control, body weight and blood pressure in patients with T2DM suboptimally controlled on metformin, and was well tolerated. | ||
信号通路 | Ion Channel/Membrane Transporter GPCR/G Protein | ||
靶 点 | SGLT |
结构式
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