Dasatinib

  • Chemical Properties
CAS No. 302962-49-8 Cat. No. BCP01797
Name Dasatinib
Synonyms BMS-354825;BMS354825;BMS 354825;
Formula C22H26ClN7O2S M. Wt 488.01
  • Biological Activity
Description Dasatinib is a selective tyrosine kinase receptor inhibitor that is used in the therapy of chronic myelogenous leukemia (CML) positive for the Philadelphia chromosome. Dasatinib is commonly associated with transient elevations in serum aminotransferase levels during treatment, but with only rare instances of clinically apparent acute liver injury.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Src/Bcr Abl 

Structure

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