SB742457
| CAS No. | 607742-69-8 | Cat. No. | BCP27653 |
| Name | SB742457 | ||
| Synonyms | Intepirdine;GSK-742457;SB-742457;SB 742457;GSK742457;GSK 742457; RVT-101; RVT 101; RVT101; | ||
| Formula | C19H19N3O2S | M. Wt | 353.44 |
| Description | SB742457 , also known as Intepirdine, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS). SB742457 shows increasing pro-cognitive effects in patients with AD. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | 5 HT Receptor/Serotonin Receptor | ||
Structure
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