Prucalopride

  • Chemical Properties
CAS No. 179474-81-8 Cat. No. BCP02177
Name Prucalopride
Synonyms R-093877;R-93877;R 093877;R 93877;R093877;R93877;
Formula C18H26ClN3O3 M. Wt 367.87
  • Biological Activity
Description Prucalopride induces contractions in a concentration-dependent manner with pEC50 of 7.5. Prucalopride (1 mM) significantly amplifies the rebound contraction of the guinea-pig proximal colon after electrical field stimulation. Prucalopride induces relaxation of the rat oesophagus preparation of rat oesophagus tunica muscularis mucosae with pEC50 of 7.8, yielding a monophasic concentration–response curve.
Related Products 179474-80-7(Prucalopride hydrochloride) 179474-85-2(Prucalopride Succinate)
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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