PJ 34 HCl
| CAS No. | 344458-15-7 | Cat. No. | BCP02366 |
| Name | PJ 34 HCl | ||
| Synonyms | PJ-34 HCl;PJ34 HCl; PARP Inhibitor VIII, PJ34;PJ-34 hydrochloride; PJ34 hydrochloride; PJ 34 hydrochloride; | ||
| Formula | C17H17N3O2HCl | M. Wt | 331.8 |
| Description | PJ34 is a potent, phenanthridinone PARS inhibitor, which is approximately 10,000 times more potent than the prototypical PARS inhibitor 3-aminobenzamide. PJ34 inhibited peroxynitrite-induced cell necrosis with EC50 of 20 nM. PJ34 provides cardioprotection by decreasing myocardial infarct size and enhancing postischemic regional and global functional recovery. | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | PARP | ||
Structure
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