LY335979
| CAS No. | 167354-41-8 | Cat. No. | BCP27664 |
| Name | LY335979 | ||
| Synonyms | LY-335979;LY 335979;Zosuquidar; D06387; RS33295198; | ||
| Formula | C32H31F2N3O2 | M. Wt | 527.6 |
| Description | Zosuquidar, also known as LY-335979, is a potent P-glycoprotein (P-gp) inhibitor, which binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). P-glycoprotein, encoded by the MDR-1 gene, is a member of the ATP-binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product-derived cytotoxic agents. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
| Targets | P glycoprotein | ||
Structure
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