Luminespib
| CAS No. | 747412-49-3 | Cat. No. | BCP01827 |
| Name | Luminespib | ||
| Synonyms | AUY922;NVP-AUY922;VER-52296;AUY 922;AUY-922;VER 52296;VER52296; | ||
| Formula | C26H31N3O5 | M. Wt | 465.54 |
| Description | Luminespib is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins. | ||
| Pathways | Protease/Metabolic Enzyme Cell Cycle/DNA Damage | ||
| Targets | HSP | ||
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Efficiency of AUY922 in mice with adult T-cell leukemia/lymphoma
Publications Citing of Biochempartner's Luminespib(CAS:747412-49-3) |
Structure
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