Pluripotin
| CAS No. | 839707-37-8 | Cat. No. | BCP02463 |
| Name | Pluripotin | ||
| Synonyms | SC1;SC 1;SC-1; | ||
| Formula | C27H25F3N8O2 | M. Wt | 551 |
| Description | In order to maintain embryonic stem cells in an undifferentiated state, it is typically necessary to use a combination of feeder cells, leukemia inhibitor factor (LIF) and bone morphogenic protein (BMP); SC1 (Pluripotin) allows for stem cell propagation in the absence of these factors. The activity of SC1 is mediated by Ras signaling which promotes self-renewal, and inhibition of ERK blocks differentiation. | ||
| Pathways | PI3K/Akt/mTOR MAPK Pathway | ||
| Targets | RSK | ||
Structure
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