Kenpaullone
| CAS No. | 142273-20-9 | Cat. No. | BCP02440 |
| Name | Kenpaullone | ||
| Synonyms | 9-BroMopaullone;NSC664704; NSC-664704; NSC 664704; | ||
| Formula | C18H17BrN2O | M. Wt | 327.18 |
| Description | Kenpaullone has been shown to inhibit GSK-3 with an IC50 value of 0.23 μM and CDK1/cyclin B, CDK2/cyclin A, CDK5/p25, and lymphocyte kinase with IC50 values of 0.4, 0.68, 0.85, and 0.47 μM, respectively. Due to the compound’s activity Kenpaullone is useful in the study of cell cycle regulators. Kenpaullone is an inhibitor of cyclin E, ERK 2 and p35. | ||
| Pathways | Cell Cycle/DNA Damage Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | GSK3 CDK | ||
Structure
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