SB216763

  • Chemical Properties
CAS No. 280744-09-4 Cat. No. BCP01764
Name SB216763
Synonyms SB-216763;SB 216763;
Formula C19H12Cl2N2O2 M. Wt 371.22
  • Biological Activity
Description SB 216763 is potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 9 nM for GSK-3α); competes with ATP. SB 216763 has minimal activity against 24 other protein kinases (IC50 > 10 μ M). Stimulates glycogen synthesis, gene transcription and is neuroprotective. SB 216763 also reduces pulmonary inflammation and fibrosis in a mouse model.
Pathways Wnt/Stem Cell PI3K/Akt/mTOR 
Targets GSK3 

Structure

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
Service & Tech Support:orders@biochempartner.com
Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.