SB743921
| CAS No. | 940929-33-9 | Cat. No. | BCP02471 |
| Name | SB743921 | ||
| Synonyms | SB-743921;SB 743921; | ||
| Formula | C31H33N2O3.HCl | M. Wt | 553.53 |
| Description | The Ki of SB 743921 for human and mouse KSP is 0.1 nM and 0.12 nM, respectively, while the Ki of SB 743921 for other kinesins including MKLP1, Kin2 is more than 70 μM. SB 743921 blocks assembly of a functional mitotic spindle, thereby causing cell cycle arrest in mitosis and subsequent cell death. SB-743921 has improved potency over ispinesib in both biochemical and cellular assays. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Kinesin | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.