Paclitaxelx

  • Chemical Properties
CAS No. 33069-62-4 Cat. No. BCP01838
Name Paclitaxelx
Synonyms BMS 181339-01; BMS181339-01; BMS-181339-01; Onxol;Nov-Onxol;
Formula C47H51NO14 M. Wt 853.91
  • Biological Activity
Description Paclitaxel is a compound with antineoplastic activity extracted from the Pacific yew tree Taxus brevifolia. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby inhibiting cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2).
Pathways Cell Cycle/DNA Damage Others Pathway 
Targets ADC Related Microtubule 

Structure

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