Anacetrapib
| CAS No. | 875446-37-0 | Cat. No. | BCP02374 |
| Name | Anacetrapib | ||
| Synonyms | MK0859;MK 0859;MK-0859; | ||
| Formula | C30H25F10NO3 | M. Wt | 637.51 |
| Description | Anacetrapib is not only able to increase HDL-cholesterol, but also further decreases LDL-cholesterol when taken in combination with a statin. Anacetrapib dose-dependently and significantly decreases the transfer of CE from HDL3 to HDL2. Anacetrapib doesn't affect the amount of [14C]-dalcetrapibthiol bound to rhCETP. Anacetrapib decreases pre-β-HDL formation by more than 46%.Anacetrapib potently blocks CE and TG transfer in 95% human serum. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | CETP | ||
Structure
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