Ko 143

  • Chemical Properties
CAS No. 461054-93-3 Cat. No. BCP02196
Name Ko 143
Synonyms Ko-143;Ko143;
Formula C26H35N3O5 M. Wt 469.57
  • Biological Activity
Description Ko 143 displays > 200-fold selectivity over P-gp and MRP-1 transporters. Ko 143 increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance.
Pathways Ion Channel/Membrane Transporter 
Targets BCRP 

Structure

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