5-氟尿嘧啶
| CAS号 | 51-21-8 | 货号 | BCP02083 |
| 中文名 | 5-氟尿嘧啶 | ||
| 英文名 | Fluorouracil | ||
| 中文别名 | |||
| 英文别名 | 5-Fluoracil;5-FU;Carac;Efudex; | ||
| 分子式 | C4H3FN2O2 | 分子量 | 130.08 |
| 生物活性 | Fluorouracil, also known as 5-Fluorouracil and 5-FU, is a medication which is used in the treatment of cancer. It is a suicide inhibitor and works through irreversible inhibition of thymidylate synthase. It belongs to the family of drugs called the antimetabolites. It is also a pyrimidine analog. Fluorouracil has been given systemically for anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers (especially head and neck cancers). It has also been given topically (on the skin) for actinic keratoses, skin cancers and Bowen's disease. | ||
| 信号通路 | Cell Cycle/DNA Damage | ||
| 靶 点 | Antimetabolite | ||
结构式
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