Valspodar
| CAS No. | 121584-18-7 | Cat. No. | BCP27698 |
| Name | Valspodar | ||
| Synonyms | PSC 833;PSC-833;PSC833; SDZ PSC 833; Sdz-psc-833; | ||
| Formula | C63H111N11O12 | M. Wt | 1214.62 |
| Description | Valspodar, also known as PSC-833, is an analogue of cyclosporin-A. Valspodar inhibits p-glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activity of some drugs in some drug-resistant tumor cells. This agent also induces caspase-mediated apoptosis. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
| Targets | P glycoprotein | ||
Structure
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