SB 612111 HCl
  • Chemical Properties
CAS No. 371980-98-2 Cat. No. BCP27704
Name SB 612111 HCl
Synonyms SB-612111;SB612111; SB 612111 HCl; SB612111 HCl;
Formula C24H29Cl2NO.HCl M. Wt 454.86
  • Biological Activity
Description SB 612111 HCl is a selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively). It antagonizes the pronociceptive action of nociceptin (Cat. No. 0910) in an acute pain model. SB 612111 HCl potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model.
Pathways Neuro Signaling Pathway Hormone Pathay GPCR/G Protein 
Targets Opioid Receptor 

Structure

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