SB 699551

  • Chemical Properties
CAS No. 791789-61-2 Cat. No. BCP02183
Name SB 699551
Synonyms SB-699551;SB699551;
Formula C34H45N3O.HCl M. Wt 584.66
  • Biological Activity
Description SB-699551 is a drug which was the first compound developed to act as a selective antagonist for the serotonin receptor 5-HT5A, with selectivity of around 100x over other serotonin receptor subtypes.The function of the 5-HT5A receptor remains poorly defined, but SB-699551 was found to modulate serotonin release from neurons, suggesting it acts as a presynaptic inhibitory autoreceptor similar to the 5-HT1B and 5-HT1D receptors.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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