Amonafide
| CAS No. | 69408-81-7 | Cat. No. | BCP01940 |
| Name | Amonafide | ||
| Synonyms | AS1413; Nafidimide; Benzisoquinolinedione; Quinamed; Xanafide; | ||
| Formula | C16H17N3O2 | M. Wt | 283.32 |
| Description | Amonafide is an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Topoisomerase | ||
Structure
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