TAK-901
| CAS No. | 934541-31-8 | Cat. No. | BCP02526 |
| Name | TAK-901 | ||
| Synonyms | TAK901;TAK 901; | ||
| Formula | C28H32N4O3S | M. Wt | 504.66 |
| Description | TAK-901 is a small-molecule inhibitor of the serine-threonine kinase Aurora B with potential antineoplastic activity. Aurora B kinase inhibitor TAK-901 binds to and inhibits the activity of Aurora B, which may result in a decrease in the proliferation of tumor cells that overexpress Aurora B. Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere; the segregation of sister chromatids to each daughter cell; and the separation of daughter cells during cytokinesis. This serine/threonine kinase may be amplified and overexpressed by a variety of cancer cell types. Check for active clinical trials or closed clinical trials using this agent. | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | Aurora | ||
Structure
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