Furosemide
| CAS No. | 54-31-9 | Cat. No. | BCP02152 |
| Name | Furosemide | ||
| Synonyms | Lasix; | ||
| Formula | C12H11ClN2O5S | M. Wt | 330.74 |
| Description | Furosemide acts by inhibiting the Na-K-2Cl symporter in the thick ascending limb of the loop of Henle. The action on the distal tubules is independent of any inhibitory effect on carbonic anhydrase or aldosterone; it also abolishes the corticomedullary osmotic gradient and blocks negative as well as positive free water clearance. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | NKCC | ||
Structure
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