AMG-47a

  • Chemical Properties
CAS No. 882663-88-9 Cat. No. BCP01962
Name AMG-47a
Synonyms AMG47a;AMG 47a;
Formula C29H28F3N5O2 M. Wt 535.56
  • Biological Activity
Description AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Src/Bcr Abl 

Structure

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