AZD8330
| CAS No. | 869357-68-6 | Cat. No. | BCP02466 |
| Name | AZD8330 | ||
| Synonyms | ARRY-424704;ARRY 424704;ARRY424704;AZD-8330;AZD 8330; | ||
| Formula | C16H17FIN3O4 | M. Wt | 461.23 |
| Description | AZD8330 potently and strongly inhibits MEK 1/2. AZD8330 has no inhibitory activity against over 200 other kinases including at concentrations up to 10 μM. AZD8330 demonstrates sub-nanomolar potency in mechanistic (pERK) and low to sub-nanomolar potency in functional (proliferation) assays in MEK 1/2 inhibitor sensitive cell lines. | ||
| Pathways | MAPK Pathway | ||
| Targets | MEK/ERK | ||
Structure
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