6-Thioguanine
CAS No. | 154-42-7 | Cat. No. | BCP27718 |
Name | 6-Thioguanine | ||
Synonyms | Thioguanine;6-TG; 2-Amino-6-mercaptopurine; 2-Amino-6-purinethiol; | ||
Formula | C5H5N5S | M. Wt | 167.19 |
Description | 6-Thioguanine is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively. | ||
Pathways | Microbiology/Virology Cell Cycle/DNA Damage | ||
Targets | SARS CoV DUB |
Structure
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