奥当卡替
CAS号 | 603139-19-1 | 货号 | BCP01830 |
中文名 | 奥当卡替 | ||
英文名 | Odanacatib | ||
中文别名 | 奥达卡替; | ||
英文别名 | MK-0822;MK 0822;MK0822; | ||
分子式 | C25H27F4N3O3S | 分子量 | 525.57 |
生物活性 | Odanacatib, also known as MK-0822, is an inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K, which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Cathepsin K, a tissue-specific cysteine protease that catalyzes degradation of bone matrix proteins such as collagen I/II, elastin, and osteonectin plays an important role in osteoclast function and bone resorption. Check for active clinical trials or closed clinical trials using this agent. | ||
信号通路 | Protease/Metabolic Enzyme | ||
靶 点 | Cathepsin |
结构式

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