Apratastat
| CAS No. | 287405-51-0 | Cat. No. | BCP27735 |
| Name | Apratastat | ||
| Synonyms | TMI-005; TMI005; TMI 005; XMT-1191; XMT 1191; XMT1191; | ||
| Formula | C17H22N2O6S2 | M. Wt | 414.5 |
| Description | Apratastat is a matrix metalloproteinase/tumour necrosis factor-α convertase (MMP/TACE) inhibitor for the treatment of rheumatoid arthritis. It inhibits secretion of soluble TNF-α and downregulates multiple MMPs, which is involved in cartilage destruction and bone erosions of RA. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | MMP | ||
Structure
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