Perindopril erbumine

  • Chemical Properties
CAS No. 107133-36-8 Cat. No. BCP27737
Name Perindopril erbumine
Synonyms Perindopril;Coversyl;ACEON; Perindopril tert-butylamine; Perstarium; Pirindopril; S 9490; S 9490 3; S 9490-3; S 94903; S-9490;
Formula C19H32N2O5.C4H11N M. Wt 441.6
  • Biological Activity
Description Perindopril Erbumine is an angiotensin-converting enzyme inhibitor. It is used in patients with hypertension and heart failure. Upon hydrolysis, perindopril erbumine is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.
Pathways Protease/Metabolic Enzyme Hormone Pathay 
Targets RAAS/ACE 

Structure

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