AEG-3482
CAS No. | 63735-71-7 | Cat. No. | BCP01890 |
Name | AEG-3482 | ||
Synonyms | AEG 3482;AEG3482; | ||
Formula | C10H8N4O2S2 | M. Wt | 280.3 |
Description | AEG 3482 has been shown to induce HSF1-dependent expression of HSP70 and HSP25 and effectively block NRAGE- and p75NTR-mediated JNK activation and apoptosis in PC12 cells in a dose-dependent manner (>90% inhibition at 40 μM). | ||
Pathways | Protease/Metabolic Enzyme Cell Cycle/DNA Damage | ||
Targets | HSP |
Structure
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