Brincidofovir

  • Chemical Properties
CAS No. 444805-28-1 Cat. No. BCP08580
Name Brincidofovir
Synonyms CMX001; CMX 001; CMX-001; HDP-cidofovir; Hexadecyloxypropyl-cidofovir; HDP-CDV; HDPCDV;
Formula C27H52N3O7P M. Wt 561.69
  • Biological Activity
Description Brincidofovir, also known as CMX001, HDP-CDV and HDPCDV, is DNA polymerase inhibitor potentially for the treatment of cytomegalovirus, adenovirus, smallpox, and ebolavirus infections. Brincidofovir is a prodrug of cidofovir. Conjugated to a lipid, the compound is designed to release cidofovir intracellularly, allowing for higher intracellular and lower plasma concentrations of cidofovir, effectively increasing its activity against dsDNA viruses, as well as oral bioavailability.
Pathways Microbiology/Virology 
Targets CMV 

Structure

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