MDL-29951
| CAS No. | 130798-51-5 | Cat. No. | BCP08592 |
| Name | MDL-29951 | ||
| Synonyms | MDL 29951;MDL29951; | ||
| Formula | C12H9Cl2NO4 | M. Wt | 302.11 |
| Description | MDL-29951 was approximately 2000-fold selective for the glycine binding site relative to the glutamate recognition sites. MDL-29951 completely inhibited the use-dependent binding of [3H]N-[1-(2-thienyl) cyclohexyl]-piperidine and was noncompetitive, glycine-reversible inhibitor of both NMDA-induced biochemical and electrophysiological responses in brain slice preparations. MDL-29951, an antagonist of the glycine site of the NMDA receptor, has been found to be an allosteric inhibitor of the enzym | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | AMPA/NMDA | ||
Structure
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