阿糖腺苷
| CAS号 | 5536-17-4 | 货号 | BCP27778 |
| 中文名 | 阿糖腺苷 | ||
| 英文名 | Vidarabine | ||
| 中文别名 | |||
| 英文别名 | Vira A; Vira-A; ViraA; Ara-A; Ara A; Arabinofuranosyladenine;Adenine Arabinoside; 9-beta-Arabinofuranosyladenine; | ||
| 分子式 | C10H13N5O4 | 分子量 | 267.25 |
| 生物活性 | Vidarabine is an antiviral drug which is active against herpes simplex and varicella zoster viruses. The drug was originally intended as an anti-cancer drug. The anti-viral activity of vidarabine was first described by M. Privat de Garilhe and J. De Rudder in 1964. It was the first nucleoside analog antiviral to be given systemically and was the first agent to be licensed for the treatment of systematic herpes virus infection in humans. It was University of Alabama at Birmingham researcher and physician Dr. Richard Whitley in 1976 where the clinical effectiveness of vidarabine was first realized, and vidarabine was used in the treatment of many viral diseases. | ||
| 信号通路 | Cell Cycle/DNA Damage Microbiology/Virology | ||
| 靶 点 | Antimetabolite HSV | ||
结构式
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