Lubiprostone
CAS No. | 333963-40-9 | Cat. No. | BCP08672 |
Name | Lubiprostone | ||
Synonyms | RU-0211; RU 0211; RU0211; Spi 0211; Spi-0211; Spi0211; | ||
Formula | C20H32F2O5 | M. Wt | 390.46 |
Description | Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). | ||
Pathways | Ion Channel/Membrane Transporter | ||
Targets | Chloride Channel |
Structure
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