Lubiprostone

  • Chemical Properties
CAS No. 333963-40-9 Cat. No. BCP08672
Name Lubiprostone
Synonyms RU-0211; RU 0211; RU0211; Spi 0211; Spi-0211; Spi0211;
Formula C20H32F2O5 M. Wt 390.46
  • Biological Activity
Description Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM).
Pathways Ion Channel/Membrane Transporter 
Targets Chloride Channel 

Structure

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