Tafluprost

  • Chemical Properties
CAS No. 209860-87-7 Cat. No. BCP08673
Name Tafluprost
Synonyms AFP168; AFP 168; AFP-168; MK-2452; MK2452; MK 2452;
Formula C25H34F2O5 M. Wt 452.53
  • Biological Activity
Description Tafluprost is a very potent FP receptor agonist, with a Ki of 0.4 nM. Tafluprost is a 2-series, 16-phenoxy analog of PGF2α with the 15,15-difluoro substitution. The ester prodrug forms of tafluprost are also potent ocular hypotensives in monkeys.
Pathways GPCR/G Protein 
Targets Prostaglandin Receptor 

Structure

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