Diphenyleneiodonium chloride

CAS No.	4673-26-1	Cat. No.	BCP08692
Name	Diphenyleneiodonium chloride
Synonyms	Dibenziodolium chloride; DPI;Diphenyleneiodonium chloride;
Formula	C12H8ClI	M. Wt	314.55

Description	Diphenyleneiodonium Chloride is an agonist of GPR3. It activates several GPR3-mediated signal transduction pathways, including Ca(2+) mobilization, cAMP accumulation, membrane recruitment of ß-arrestin2, and receptor desensitization. Diphenyleneiodonium Chloride also acts as a potent and reversible inhibitor of nitric oxide synthetase from macrophages and endothelial cells, and inhibits other flavoenzymes such as neutrophil NADPH oxidase.
Pathways	Ion Channel/Membrane Transporter Protease/Metabolic Enzyme
Targets	TRP Channel NOX

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