Naproxcinod

  • Chemical Properties
CAS No. 163133-43-5 Cat. No. BCP08710
Name Naproxcinod
Synonyms Naproxen-N-butyl nitrate; Nitronaproxen; AZD 3582; AZD-3582; AZD3582; HCT3012; HCT-3012; HCT 3012; AR-P-900758XX; NO-naproxen;
Formula C18H21NO6 M. Wt 347.36
  • Biological Activity
Description Naproxcinod is a nitric oxide-releasing NSAID derivative. Naproxcinod significantly ameliorated skeletal muscle force and resistance to fatigue in sedentary as well as in exercised mice, reduced inflammatory infiltrates and fibrosis deposition in both cardiac and diaphragm muscles. Conversely, the equimolar dose of naproxen showed no effects on fibrosis and improved muscle function only in sedentary mice. In addition to anti-inflammatory activity, naproxcinod as a promising candidate for treatment of Duchenne Muscular Dystrophy.
Pathways Neuro Signaling Pathway 
Targets COX 

Structure

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
Service & Tech Support:orders@biochempartner.com
Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.