AN-2690

  • Chemical Properties
CAS No. 174671-46-6 Cat. No. BCP08730
Name AN-2690
Synonyms Tavaborole; AN2690; AN 2690; Kerydin;
Formula C7H6BFO2 M. Wt 151.93
  • Biological Activity
Description AN-2690, a broad-spectrum drug, is a very promising candidate for treatment of ungual and periungual infections with improved nail penetration and low keratin binding. AN-2690 is an antifungal agent with activity against Trichophyton species. AN-2690 inhibits yeast cytoplasmic leucyl-tRNA synthetase by formation of a stable tRNA(Leu)-AN2690 adduct in the editing site of the enzyme. AN-2690 is currently in clinical trials for onychomycosis topical treatment.
Pathways Microbiology/Virology 
Targets Antifungal 

Structure

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