BMS-863233 HCl salt
| CAS No. | 1169562-71-3 | Cat. No. | BCP08741 |
| Name | BMS-863233 HCl salt | ||
| Synonyms | BMS-863233; BMS863233; BMS 863233; XL-413; XL413; XL 413; | ||
| Formula | C14H13Cl2N3O2 | M. Wt | 326.18 |
| Description | BMS-863233, also known as XL-413, is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. CDC7 kinase inhibitor BMS-863233 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA replication and mitosis, the induction of tumor cell apoptosis, and the inhibition of tumor cell proliferation in CDC7-overexpressing tumor cells. CDC7, a serine-threonine kinase overexpressed in a variety of tumor cell types | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | CDK | ||
Structure
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