Eprosartan Myslate

  • Chemical Properties
CAS No. 144143-96-4 Cat. No. BCP27833
Name Eprosartan Myslate
Synonyms Teveten; Futuran; Navixen; Regulaten; SKF 108566; SKF-108566;
Formula C24H28N2O7S2 M. Wt 520.62
  • Biological Activity
Description Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. It is marketed in the United States as Teveten by Abbvier. Eprosartan is sometimes paired with hydrochlorothiazide, whereupon it is marketed in the US as Teveten HCT and elsewhere as Teveten Plus.The drug acts on the renin-angiotensin system to decrease total peripheral resistance in two ways. First, it blocks the binding of angiotensin II to AT1 receptors in vascular smooth muscle, causing vascular dilatation. Second, it inhibits sympathetic norepinephrine production, further reducing blood pressure. As with other angiotensin II receptor antagonists, eprosartan is generally better tolerated than enalapril (an ACE inhibitor), especially among the elderly.
Pathways GPCR/G Protein 
Targets Angiotensin Receptor 

Structure

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