CZC24832
| CAS No. | 1159824-67-5 | Cat. No. | BCP08888 |
| Name | CZC24832 | ||
| Synonyms | CZC-24832; CZC 24832; | ||
| Formula | C15H17FN6O2S | M. Wt | 364.4 |
| Description | Selective inhibitor of PI 3-kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay). Exhibits limited off-target effects in kinome profiling of 154 identified lipid and protein kinases and 922 other proteins. Orally effective in a rodent model of inflammatory disease. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
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