Apilimod
| CAS No. | 541550-19-0 | Cat. No. | BCP27874 |
| Name | Apilimod | ||
| Synonyms | STA-5326; STA5326; STA 5326; Apilimod free base; | ||
| Formula | C23H26N6O2 | M. Wt | 418.50 |
| Description | Apilimod, also known as STA-5326, is a IL-12/IL-23 inhibitor. Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL-12 and IL-23 production by the drug. | ||
| Pathways | Others Pathway | ||
| Targets | Interleukin Related | ||
Structure
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