IWP-L6
| CAS No. | 1427782-89-5 | Cat. No. | BCP08956 |
| Name | IWP-L6 | ||
| Synonyms | IWP L6; IWPL6; | ||
| Formula | C25H20N4O2S2 | M. Wt | 472.58 |
| Description | Potent inhibitor of Porcupine (Porcn), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM). Shown to inhibit Wnt-dependent processes such as tailfin regeneration and posterior axis formation in zebrafish; also reduces branching morphogenesis in cultured mouse embryonic kidneys | ||
| Pathways | Wnt/Stem Cell | ||
| Targets | Porcupine | ||
Structure
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